Description
This book describes the essential aspects of enantioselective catalysis in a clear, logical fashion, with chapters organized by concept rather than by reaction type. Each concept in Fundamentals of Asymmetric Catalysis is supported by carefully selected examples of a wide range of catalysts, reactions and reaction mechanisms. PATRICK J. WALSH is a Professor of Chemistry at University of Pennsylvania, USA MARISA C. KOZLOWSKI is a Professor of Chemistry at University of Pennsylvania, USA Foreword.- Introduction to Fundamentals of Asymmetric Catalysis.- Modes of Asymmetric Induction.- Lewis Acid and Lewis Base Catalysis .- Beyond Lewis Acid and Lewis Base Catalyzed Activation .- Asymmetric Induction in Enantioselective Catalysis .- Nonclassical Catalyst Substrate Interactions .- Chiral Poisoning, Chiral Activation, and Screening Achiral Ligands .- Kinetic Resolution .- Parallel Kinetic Resolution .- Dynamic Kinetic Resolution and Dynamic Kinetic Asymmetric Transformations .- Desymmetrization Reactions .- Nonlinear Effects, Autocatalysis, and Autoinduction .- Bifunctional, Dual, and Multifunctional Catalyst Systems .- Asymmetric Catalysis with Enantiopure Substrates: Double Diastereoselection .- Multistep Asymmetric Catalysis .- Supported Chiral Catalysts .- Applications of Asymmetric Catalysis in Synthesis .- Appendix: Terms & Enantioselective Processes in Asymmetric Catalysis .- Index.
