Description
Discusses how to fightA Ebola, SARS Corona,A and other known or emerging human viruses by building on the successes in antiviral therapy of the past decadesA Written by leading medicinal chemists from academia and industry, thisA bookA discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets,A and viral disease mechanisms.A ItA providesA an outlook on emerging pathogens such as Ebola,A Zika,A West Nile, Lassa,A and includes aA chapterA onA SARSA Coronoavirus-2 causing the presentA pandemic.A A New Drug Development for Known and Emerging VirusesA describes the discovery and development process for antiviral agents for different classes of viruses and targets based on theA experiencesA from the nine human viruses for which approved drugs are on the market (HIV, HCV, Influenza, RSV, HBV, HPV, HCMV, HSV,A andA VZV). It covers theA properties and potential of 20 classes of currently approved antivirals,A including combination drugs, and looks at novel antiviral strategies against emerging viruses.A Covers theA entire field of antiviral drug discovery and developmentA A AddressesA theA need forA antiviral drugsA to combatA majorA healthA threatsA such asA Ebola, Zika,A West Nile, andA SARS Coronavirus-2A Summarizes the successes of the past 15 years in developing ground-breaking medicines against 9 major human viruses, both from the medicinal chemistry and the pharmacological angleA DiscussesA practical and strategic challenges in the drug discovery and development process, including screening technologies, latency,A and toxicity issuesA New Developments in Antiviral DrugsA is anA importantA book forA medicinal chemists, pharmaceutical chemists, virologists,A andA epidemiologists, and willA be of great interest to those in theA pharmaceutical industryA andA public health agencies.A
