Description
Fundiert, verstndlich, anwendungsorientiert: Im Lehrbuchstil verfasst, fhrt das Werk so in die Massenspektrometrie ein, dass seine Leser nach grndlicher Lektre in der Lage sind, die hier vorgestellten Techniken – insbesondere moderne Massenspektrometer – im Labor einzusetzen. Preface. Acknowledgements. 1 Measurement, Dimensions and Units. 2 Tools of the Trade I. The Classical Tools. 3 Tools of the Trade II. Theory of Chromatography. Appendix 3.1 Derivation of the Plate Theory Equation for Chromatographic Elution. Appendix 3.2 Transformation of the Plate Theory Elution Equation from Poisson to Gaussian Form. Appendix 3.3 A Brief Introduction to Snyder’s Theory of Gradient Elution. List of Symbols Used in Chapter 3. 4 Tools of the Trade III. Separation Practicalities. Appendix 4.1 Responses of Chromatographic Detectors: Concentration vs Mass-Flux Dependence. 5 Tools of the Trade IV. Interfaces and Ion Sources for Chromatography-Mass Spectrometry. 6 Tools of the Trade V. Mass Analyzers for Quantitation: Separation of Ions by m/z Values. Appendix 6.1 Interaction of Electric and Magnetic Fields with Charged Particles. Appendix 6.2 Leak Detection. Appendix 6.3 List of Symbols Used in Chapter 6. 7 Tools of the Trade VI. Ion Detection and Data Processing. 8 Tools of the Trade VII: Statistics of Calibration, Measurement and Sampling. Appendix 8.1 A Brief Statistics Glossary. Appendix 8.2 Symbols Used in Discussion of Calibration Methods. 9 Method Development and Fitness for Purpose. 10 Method Validation and Sample Analysis in a Controlled Laboratory Environment. 11 Examples from the Literature. Epilog. References. Index.
